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Seminar 16 & 17 October 2014

Advanced LC Method Development Seminar 2014:
Best Proctices for HPLC and UHPLC
with world renowned
Dr. John Dolan (of LC Resources)

To avoid disappointment, please book immediately. Seminar is limited to max. 15 participants

The Lecturer

Dr John Dolan is an acclaimed chromatography expert with over 25 years experience as one of the best HPLC trainers in the world. His presentations are non-commercial, very practical and of very high standard. This workshop is ideal for practising chromatographers who would like to improve their work effectiveness and efficiency. Attendees will gain practical skills to develop realistic HPLC methods in a short time. It will be a two-day course and interactive with participants’ special needs.

Who should take this course?

This workshop is ideal for practising chromatographers who would like to improve their work effectiveness and efficiency. Attendees will gain practical skills to develop realistic HPLC methods in a short time. It will be a two-day course and interactive with participants’ special needs. This course is for chromatographers who want to develop better methods faster and less expensively. This course also discusses new technologies and trends.

What does it cover?

A comprehensive course in liquid chromatography
method development using Quality by Design (QbD)

The central tenant of Quality by Design (ICH Q8) is that quality cannot be tested into a product – instead it must be designed into the product. When the product is an HPLC or UHPLC method, QbD strategies can guide the development process to result in a standardized method development process, more easily validated methods, and methods that are easier to use and adjust in routine applications.

UHPLC is one of the buzz-words in the liquid chromatography (LC) laboratory today, but it really is just an extension of traditional HPLC -- with higher pressures and smaller particles. Our Advanced HPLC Method Development course has been revised to include both HPLC and UHPLC – to point out where they are the same, where they are different, and how to take maximum advantage of each technology.

This 2- day class is designed for laboratory workers involved in HPLC or UHPLC method development as well as those who must transfer of existing methods into a routine laboratory. The class focuses on separation fundamentals and applies them in a time-proven strategy that applies QbD principles to developing robust LC methods quickly. Based on the instructor’s extensive experience in a laboratory supporting pharmaceutical and bioanalytical methods, the attendees should gain practical skills to develop realistic LC methods in a short time. The techniques can be used as a stand-alone strategy or added to existing development procedures to help streamline the process. The course content assumes a basic understanding of LC, but not necessarily experience in method development.  Students will be introduced to LC method development software to help find satisfactory separation conditions. Attendees will receive a comprehensive set of course notes, including copies of all visual materials presented.

Contents

Day 1 : 16. October 2014

  • Section 1 – Introduction to LC Method Development
  • Section 2 – LC Basics
  • Section 3 – Columns
  • Section 4 – Reversed-Phase Separation
  • Section 5 – Dealing with Ionic Samples
  • Section 6 – Equivalent and Orthogonal Columns

Day 2 : 17. October 2014

  • Section 7 – Gradient Elution
  • Section 8 – UHPLC Considerations
  • Section 9 – Quality by Design
  • Bonus Options
  • Normal Phase and HILIC
  • Chiral Separations
  • Ion-Exchange Chromatography
  • Quality Issues
  • LC-MS Basics
  • Sample Preparation

The normal class covers Sections 1-9. Depending on the interests of the particular group of attendees and the remaining time, one or more of the Bonus topics may be included. Each student receives a course notebook, which contains copies of all the slides used in the class plus a written summary of the key points for each slide.

This course makes use of chromatography simulation software as a teaching tool. The principles used in computer modeling are fully applicable to separations in your lab. You will learn how to do the best possible chromatography. Save hours of frustration and improve your results time after time.

Our main goal is not to get through a canned curriculum, but to provide practical help to attendees that can be applied in real situations in the lab. Students are encouraged to bring questions, separations problems, and other topics of interest to discuss during the class or one-on-one with the instructor.

Note:

  • A Certificate on Advanced HPLC Method Development by Jon Dolan will be issued after completing the course
  • Interested participants are encouraged to bring questions, separations problems, and other topics of interest to discuss during the class or one-on-one with the instructor.

Venue:
Historically famous ‘Alte Mühle’, Bahnhofstrasse, CH 4622
Egerkingen
.  Alte Mühle is ca. 400 years old building located beside the Gemeinde Haus in the center of the village. It can be easily reached by car (plenty of parking space) and 5 minute walk from the train station or bus stop

Seminar Cost:
Two days: CHF. 1900.-
Covers course materials, refreshment and meals (incl.dinner for
the 2 day course)

Registration

To register please send us your email to info at chromatographyshop dot com or through the Contact Page. Alternatively, contact us by phone on +41 62 398 52 71.

Photos

 

Participants 2014: Ask for original copies. Pictures below are reduced and compressed

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